Deep mutational scanning: assessing protein function on a massive scale
- 30 September 2011
- journal article
- review article
- Published by Elsevier BV in Trends in Biotechnology
- Vol. 29 (9), 435-442
- https://doi.org/10.1016/j.tibtech.2011.04.003
Abstract
No abstract availableKeywords
This publication has 72 references indexed in Scilit:
- Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchipsNature Biotechnology, 2010
- Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndromeNature Genetics, 2010
- A three-dimensional model of the yeast genomeNature, 2010
- High-resolution analysis of DNA regulatory elements by synthetic saturation mutagenesisNature Biotechnology, 2009
- Targeted capture and massively parallel sequencing of 12 human exomesNature, 2009
- HITS-CLIP yields genome-wide insights into brain alternative RNA processingNature, 2008
- Somatic mutations affect key pathways in lung adenocarcinomaNature, 2008
- Genome-wide maps of chromatin state in pluripotent and lineage-committed cellsNature, 2007
- Patterns of somatic mutation in human cancer genomesNature, 2007
- Robustness–epistasis link shapes the fitness landscape of a randomly drifting proteinNature, 2006