Programming DNA Tube Circumferences
- 8 August 2008
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 321 (5890), 824-826
- https://doi.org/10.1126/science.1157312
Abstract
Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.Keywords
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