Anticancer and Antifungal Compounds from Aspergillus, Penicillium and Other Filamentous Fungi
Open Access
- 13 September 2013
- Vol. 18 (9), 11338-11376
- https://doi.org/10.3390/molecules180911338
Abstract
This review covers important anticancer and antifungal compounds reported from filamentous fungi and in particular from Aspergillus, Penicillium and Talaromyces. The taxonomy of these fungi is not trivial, so a focus of this review has been to report the correct identity of the producing organisms based on substantial previous in-house chemotaxonomic studies.This publication has 200 references indexed in Scilit:
- Fungal Origins of the Bicyclo[2.2.2]diazaoctane Ring System of Prenylated Indole AlkaloidsJournal of Natural Products, 2012
- Caspase-1 Inhibitors from an Extremophilic Fungus That Target Specific Leukemia Cell LinesJournal of Natural Products, 2012
- Genetics of Polyketide Metabolism in Aspergillus nidulansMetabolites, 2012
- The Selectivity of Austocystin D Arises from Cell-Line-Specific Drug Activation by Cytochrome P450 EnzymesJournal of Natural Products, 2011
- Fungal Indole Alkaloid Biosynthesis: Genetic and Biochemical Investigation of the Tryptoquialanine Pathway in Penicillium aethiopicumJournal of the American Chemical Society, 2011
- Lovastatin induces apoptosis of ovarian cancer cells and synergizes with doxorubicin: potential therapeutic relevanceBMC Cancer, 2010
- The use of secondary metabolite profiling in chemotaxonomy of filamentous fungiMycological Research, 2008
- The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cellsBMC Cancer, 2008
- Taxonomic revision of Aspergillus section Clavati based on molecular, morphological and physiological dataStudies in Mycology, 2007
- HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosisLeukemia, 2002