Timing of Solid Food Introduction and Risk of Obesity in Preschool-Aged Children
Top Cited Papers
- 1 March 2011
- journal article
- research article
- Published by American Academy of Pediatrics (AAP) in PEDIATRICS
- Vol. 127 (3), e544-e551
- https://doi.org/10.1542/peds.2010-0740
Abstract
OBJECTIVE: To examine the association between timing of introduction of solid foods during infancy and obesity at 3 years of age. METHODS: We studied 847 children in Project Viva, a prospective pre-birth cohort study. The primary outcome was obesity at 3 years of age (BMI for age and gender ≥95th percentile). The primary exposure was the timing of introduction of solid foods, categorized as z score from 0 to 4 months–a marker of early infant growth. RESULTS: In the first 4 months of life, 568 infants (67%) were breastfed and 279 (32%) were formula-fed. At age 3 years, 75 children (9%) were obese. Among breastfed infants, the timing of solid food introduction was not associated with odds of obesity (odds ratio: 1.1 [95% confidence interval: 0.3–4.4]). Among formula-fed infants, introduction of solid foods before 4 months was associated with a sixfold increase in odds of obesity at age 3 years; the association was not explained by rapid early growth (odds ratio after adjustment: 6.3 [95% confidence interval: 2.3–6.9]). CONCLUSIONS: Among formula-fed infants or infants weaned before the age of 4 months, introduction of solid foods before the age of 4 months was associated with increased odds of obesity at age 3 years.This publication has 28 references indexed in Scilit:
- Predictors of the early introduction of solid foods in infants: results of a cohort studyBMC Pediatrics, 2009
- Weight Status in the First 6 Months of Life and Obesity at 3 Years of AgePEDIATRICS, 2009
- Recommendations for Prevention of Childhood ObesityPEDIATRICS, 2007
- Assessment of Child and Adolescent Overweight and ObesityPEDIATRICS, 2007
- Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary ReportPEDIATRICS, 2007
- Early life risk factors for obesity in childhood: cohort studyBMJ, 2005
- Maternal Calcium Intake and Offspring Blood PressureCirculation, 2004
- Trial on Timing of Introduction to Solids and Food Type on Infant GrowthPEDIATRICS, 1998
- Influence of early feeding style on adiposity at 6 years of ageThe Journal of Pediatrics, 1990
- Do breast-feeding and delayed introduction of solid foods protect against subsequent obesity?The Journal of Pediatrics, 1981