The Incidence and Risk of Venous Thromboembolism Associated With Cancer and Nonsurgical Cancer Treatment
- 1 January 2009
- journal article
- review article
- Published by Informa UK Limited in Cancer Investigation
- Vol. 27 (1), 105-115
- https://doi.org/10.1080/07357900802563028
Abstract
Patients with cancer are at high risk of developing venous thromboembolism, a risk that varies according to the type of malignancy and its disease stage, and is steadily increased by concomitant patient-related thrombotic risk factors, such as advanced age, infection, heart disease, respiratory disease, as well as hospitalization, surgical, and nonsurgical cancer treatments. Current evidence-based guidelines raise awareness of the importance of thromboprophylaxis in hospitalized cancer patients and highlight the thrombotic risks of combined chemotherapy regimens. Therefore, they recommend that all patients hospitalized or bedridden owing to cancer should be considered for thromboprophylaxis in the absence of contraindications to anticoagulant therapy.Keywords
This publication has 77 references indexed in Scilit:
- Development and validation of a predictive model for chemotherapy-associated thrombosisBlood, 2008
- Venous Thromboembolism and Mortality Associated With Recombinant Erythropoietin and Darbepoetin Administration for the Treatment of Cancer-Associated AnemiaJAMA, 2008
- Trousseau's syndrome: multiple definitions and multiple mechanismsBlood, 2007
- Venous Thromboembolism in the Outpatient SettingArchives of Internal Medicine, 2007
- Phase III Clinical Trial of Thalidomide Plus Dexamethasone Compared With Dexamethasone Alone in Newly Diagnosed Multiple Myeloma: A Clinical Trial Coordinated by the Eastern Cooperative Oncology GroupJournal of Clinical Oncology, 2006
- Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early breast cancer: first results of the ATAC randomised trialThe Lancet, 2002
- A Comparison of Enoxaparin with Placebo for the Prevention of Venous Thromboembolism in Acutely Ill Medical PatientsNew England Journal of Medicine, 1999
- Incidence and risk of thromboembolism during treatment of high-grade gliomas: a prospective studyEuropean Journal Of Cancer, 1997
- A Randomized Clinical Trial Evaluating Tamoxifen in the Treatment of Patients with Node-Negative Breast Cancer Who Have Estrogen-Receptor–Positive TumorsNew England Journal of Medicine, 1989
- The Thrombogenic Effect of Anticancer Drug Therapy in Women with Stage II Breast CancerNew England Journal of Medicine, 1988