As the Partnership for a New Generation of Vehicles (PNGV) has been proceeding with the development of designs for high-fuel-economy vehicles, it also has been assessing whether impediments exist to the transition to these vehicles. Toward that end, as materials options and vehicle designs have been developed, Oak Ridge National Laboratory (ORNL) has been conducting analyses related to the attendant materials infrastructure requirements. This report addresses the question, what are the infrastructure requirements, acceptance issues, and life-cycle impacts associated with PNGV vehicles constructed of lightweight materials.