A POTENT NEW β2‐ADRENOCEPTOR BLOCKING AGENT
Open Access
- 19 July 1977
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 60 (3), 357-362
- https://doi.org/10.1111/j.1476-5381.1977.tb07508.x
Abstract
1 (t-Butyl-amino-3-ol-2-propyl) oximino-9 fluorene is a new β2-adrenoceptor blocking agent with a pA2 of 9.23 ± 0.25 on isolated trachea. 2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally induced by isoprenaline infusion.Keywords
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