A developmental switch in the signaling cascades for LTP induction
- 2 December 2002
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature Neuroscience
- Vol. 6 (1), 15-16
- https://doi.org/10.1038/nn985
Abstract
Long-term potentiation (LTP) is thought to be critically involved not only in learning and memory, but also during the activity-dependent developmental phases of neural circuit formation and refinement1,2. Whether the mechanisms underlying LTP change during this phase of postnatal development, however, is unknown. We report here that, unlike LTP in the more mature CA1 region of the hippocampus, LTP in neonatal rodent hippocampus (2+/calmodulin-dependent protein kinase II (CaMKII).This publication has 15 references indexed in Scilit:
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