Investigation of glycine α-ketoamide HCV NS3 protease inhibitors: Effect of carboxylic acid isosteres
- 1 August 2005
- journal article
- research article
- Published by Elsevier BV in Bioorganic & Medicinal Chemistry Letters
- Vol. 15 (15), 3487-3490
- https://doi.org/10.1016/j.bmcl.2005.06.003
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- Recent developments in target identification against hepatitis C virusEmerging Therapeutic Targets, 2004
- New therapies on the horizon for hepatitis C: are we close?Clinics in Liver Disease, 2003
- Recent developments in the discovery of hepatitis C virus serine protease inhibitors – towards a new class of antiviral agents?Expert Opinion on Investigational Drugs, 2003
- Inhibition of the Hepatitis C Virus NS3/4A ProteasePublished by Elsevier BV ,2000
- Hepatitis C Virus-Encoded Enzymatic Activities and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In VivoJournal of Virology, 2000
- Solution Structure of Substrate-based Ligands When Bound to Hepatitis C Virus NS3 Protease DomainPublished by Elsevier BV ,1999
- The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapyJournal of Viral Hepatitis, 1999
- Molecular Targets in Inhibition of Hepatitis C Virus ReplicationAntiviral Chemistry and Chemotherapy, 1997
- Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNAScience, 1997
- The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding SiteCell, 1996