The RECOVERY Platform

Abstract

In a platform trial, patients with a single disease are randomly assigned to a group of different therapies on the basis of a decision algorithm to determine whether any therapy has benefit.¹ The principle underpinning such trials allows for the execution of efficient, less expensive designs by enrolling populations quickly and collecting minimal data to answer more than one question. These are sensible principles and, when successful, result in trials that provide clear answers to several questions in a timely and efficient way.