A TrkB–STAT3–miR-204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells
Open Access
- 9 December 2013
- journal article
- Published by Springer Science and Business Media LLC in Molecular Cancer
- Vol. 12 (1), 155
- https://doi.org/10.1186/1476-4598-12-155
Abstract
We previously identified TrkB as an oncogene involved in promoting metastasis in endometrial carcinoma (EC). Here, we sought to delineate the effect of changes in TrkB expression on the global profile of microRNAs (miRNAs) in EC cells and further investigated the correlation between the expression of certain miRNA and TrkB in the clinicopathologic characteristics of EC patients.Keywords
This publication has 56 references indexed in Scilit:
- A novel epigenetic CREB‐miR‐373 axis mediates ZIP4‐induced pancreatic cancer growthEMBO Molecular Medicine, 2013
- Integrated genomic characterization of endometrial carcinomaNature, 2013
- VHL-Regulated MiR-204 Suppresses Tumor Growth through Inhibition of LC3B-Mediated Autophagy in Renal Clear Cell CarcinomaCancer Cell, 2012
- Role for miR-204 in human pulmonary arterial hypertensionThe Journal of Experimental Medicine, 2011
- miR-204 is required for lens and retinal development via Meis2 targetingProceedings of the National Academy of Sciences of the United States of America, 2010
- Epigenetics in cancerCarcinogenesis: Integrative Cancer Research, 2009
- Distinctive microRNA signature of acute myeloid leukemia bearing cytoplasmic mutated nucleophosminProceedings of the National Academy of Sciences of the United States of America, 2008
- Stat3 activation in human endometrial and cervical cancersBritish Journal of Cancer, 2007
- MicroRNA expression profiles classify human cancersNature, 2005
- Combinatorial microRNA target predictionsNature Genetics, 2005