Tn 125 -Related Acquisition of bla NDM -Like Genes in Acinetobacter baumannii
- 1 February 2012
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 56 (2), 1087-1089
- https://doi.org/10.1128/aac.05620-11
Abstract
A multidrug-resistant Acinetobacter baumannii isolate recovered from a patient hospitalized in Switzerland after a transfer from Serbia produced the NDM-1 carbapenemase. The bla NDM-1 gene was part of a chromosomally located Tn 125 composite transposon bracketed by two copies of the same insertion sequence, IS Aba125 . This transposon was also associated with the acquisition and expression of the bla NDM-2 gene in an A. baumannii isolate in Germany. Tn 125 appears to be the main vehicle for dissemination of bla NDM genes in that species.Keywords
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