Changes in Protein Levels in Perfusates of Freely Moving Cats: Relation to Behavioral State
- 14 March 1975
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4180), 963-965
- https://doi.org/10.1126/science.167436
Abstract
Perfusates from the brains of freely moving cats, obtained by means of a push-pull cannula, contain high concentrations of proteins. The levels vary in a cyclic fashion and are higher during rapid eye movement sleep than during the waking state. The proteins represent a distinctive class of tissue protein and their changing levels appear to reflect an alteration in the protein content of the extracellular space of brain related to behavioral state.Keywords
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