Optic Neuropathy Preceding Acute Retinal Necrosis in Acquired Immunodeficiency Syndrome
- 1 December 1996
- journal article
- case report
- Published by American Medical Association (AMA) in American Journal of Ophthalmology
- Vol. 114 (12), 1481-1485
- https://doi.org/10.1001/archopht.1996.01100140679005
Abstract
Objective: To describe the clinical course of varicellazoster optic neuropathy preceding acute retinal necrosis in patients with acquired immunodeficiency syndrome. Design: Case series. Setting: Two tertiary care centers in San Diego, Calif, and London, England. Patients: Three human immunodeficiency virus-positive men with previous cutaneous zoster infection, optic neuropathy, and necrotizing retinitis. Results: All patients had an episode of zoster dermatitis treated with acyclovir. Visual loss consistent with an optic neuropathy ensued, followed by typical herpetic retinitis. The cause of visual loss was not suspected to be varicella-zoster until after the retinitis occurred. Despite aggressive medical treatment, 4 of 6 eyes progressed to retinal detachment. Conclusions: Varicella-zoster may cause an optic neuropathy in patients with acquired immunodeficiency syndrome, especially in those with previous shingles. A high index of suspicion is necessary to establish the diagnosis and begin early antizoster treatment.Keywords
This publication has 7 references indexed in Scilit:
- Acute Retinal Necrosis and Similar Retinitis SyndromesInternational Ophthalmology Clinics, 1993
- Ocular Histoplasmosis with Retinitis in a Patient with Acquired Immune Deficiency SyndromeOphthalmology, 1991
- Toxoplasma gondii Retinochoroiditis and Optic Neuritis in Acquired Immune Deficiency SyndromeOphthalmology, 1990
- Herpes Zoster Optic Neuritis in Human Immunodeficiency Virus InfectionAmerican Journal of Ophthalmology, 1990
- Severe Visual Loss Related to Isolated Peripapillary Retinal and Optic Nerve Head Cytomegalovirus InfectionAmerican Journal of Ophthalmology, 1989
- Cytomegalovirus Retinitis and Optic Neuritis in Acquired Immune Deficiency SyndromeOphthalmology, 1987
- Optic Nerve Involvement in the Acute Retinal Necrosis SyndromeAmerican Journal of Ophthalmology, 1985