STABILITY OF A NOVEL DITHRANOL OINTMENT FORMULATION, CONTAINING ASCORBYL PALMITATE AS AN ANTI-OXIDANT

Abstract

An emulsifying ointment-based dithranol formulation is described which was, with the addition of 0.1% w/w ascorbyl palmitate, stable for 52 weeks at room temperature. This is in contrast to the more conventionally used dithranol in Lassar's paste, which is stable for only 4 weeks at room temperature. An emulsifying ointment-based paste was additionally more convenient to use since it was easier to apply and remove.