A psychophysiological test was developed to detect a specific behavior pattern previously found to be associated with a high incidence of clinical coronary artery disease. This test consisted of the polygraph recording of various physiological reactions of subjects listening to a specially designed tape recording of two monologues. The test appeared to differentiate the patient with clinical coronary artery disease from the normal subject. It is suggested that tests of this sort, designed for mass application, would help to identify persons with the type of personality that predisposes to high serum cholesterol levels, faster clotting times, arcus senilis, and coronary heart disease.