Efficient Ce(NO3)3·6H2O-Catalyzed Solvent-Free Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones

Abstract
Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a β-keto ester or β- diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)- ones or –thiones in excellent yields.

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