Pancreatic Tumor Cells with Mutant K-ras Suppress ERK Activity by MEK-Dependent Induction of MAP Kinase Phosphatase-2
- 1 February 2001
- journal article
- Published by Elsevier BV in Biochemical and Biophysical Research Communications
- Vol. 280 (4), 992-997
- https://doi.org/10.1006/bbrc.2001.4243
Abstract
No abstract availableKeywords
This publication has 18 references indexed in Scilit:
- Understanding Ras: ‘it ain’t over ’til it’s over’Trends in Cell Biology, 2000
- Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutationLeukemia, 1999
- Differential contribution of the ERK and JNK mitogen-activated protein kinase cascades to Ras transformation of HT1080 fibrosarcoma and DLD-1 colon carcinoma cellsOncogene, 1999
- Repression of mitogen-activated protein kinases ERK1/ERK2 activity by a protein tyrosine phosphatase in rat fibroblasts transformed by upstream oncoproteinsJournal of Cellular Physiology, 1998
- Ras target proteins in eukaryotic cellsThe FASEB Journal, 1995
- Raf meets Ras: completing the framework of a signal transduction pathwayTrends in Biochemical Sciences, 1994
- Frequent Glycine‐to‐Aspartic Acid Mutations at Codon 12 of c‐Ki‐ras Gene in Human Pancreatic Cancer in JapaneseJapanese Journal of Cancer Research, 1990
- Frequency and Types of Point Mutation at the 12th Codon of the c‐Ki‐ras Gene Found in Pancreatic Cancers from Japanese PatientsJapanese Journal of Cancer Research, 1989
- High frequency of Ki‐ras codon 12 mutations in pancreatic adenocarcinomasInternational Journal of Cancer, 1989
- Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genesCell, 1988