Voltage-Dependent Calcium and Potassium Ion Conductances: A Contingency Mechanism for an Associative Learning Model
- 24 August 1979
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 205 (4408), 810-816
- https://doi.org/10.1126/science.223244
Abstract
Persistent light-induced depolarization results from Ca2+ influx across a photoreceptor membrane. The marked dependence on potential of this Ca2+ influx and a Ca+-dependent K+ efflux accounts for enhancement of the light-induced depolarization when light is paired with rotation. A positive feedback cycle between light-induced depolarization and synaptic depolarization due to stimulus pairing can explain long-lasting behavioral changes produced by associative training but not control paradigms. The sensitivity of this Ca2+ influx to intracellular levels of adenosine 3'-5'-monophosphate suggests biochemical steps for this model of associative learning.Keywords
This publication has 38 references indexed in Scilit:
- Spin-label techniques for monitoring macromolecular rotational motion: empirical calibration under nonideal conditionsBiochemistry, 1979
- Postsynaptic modulation of excitatory process in sympathetic ganglia by cyclic AMPNature, 1978
- Signal transformation with pairing of sensory stimuli.The Journal of general physiology, 1976
- CALCIUM AND CAMP AS INTERRELATED INTRACELLULAR MESSENGERS*Annals of the New York Academy of Sciences, 1975
- Neural correlates of associative training in Hermissenda.The Journal of general physiology, 1975
- Cyclic AMP stimulation of calcium efflux from kidney, liver, and heart mitochondriaThe Journal of Membrane Biology, 1974
- Insulin secretion: Multifactorial regulation for a single process of releaseDiabetologia, 1973
- Neural Organization of a Molluscan Visual SystemThe Journal of general physiology, 1973
- Responses of Photoreceptors in Hermissenda The Journal of general physiology, 1972
- Some morphological aspects of the visual system of Hermissenda crassicornis (mollusca: nudibranchia)Journal of Ultrastructure Research, 1969