Risk factors for respiratory syncytial virus bronchiolitis hospital admission in New Zealand
- 4 January 2008
- journal article
- Published by Cambridge University Press (CUP) in Epidemiology and Infection
- Vol. 136 (10), 1333-1341
- https://doi.org/10.1017/s0950268807000180
Abstract
SUMMARY This study assessed risk factors for respiratory syncytial virus (RSV) hospitalization and disease severity in Wellington, New Zealand. During the southern hemisphere winter months of 2003–2005, 230 infants aged <24 months hospitalized with bronchiolitis were recruited. RSV was identified in 141 (61%) infants. Comparison with data from all live hospital births from the same region (2003–2005) revealed three independent risk factors for RSV hospitalization: birth between February and July [adjusted risk ratio (aRR) 1·62, 95% confidence interval (CI) 1·15–2·29], gestation <37 weeks (aRR 2·29, 95% CI 1·48–3·56) and Māori ethnicity (aRR 3·64, 95% CI 2·27–5·85) or Pacific ethnicity (aRR 3·60, 95% CI 2·14–6·06). The high risk for Māori and Pacific infants was only partially accounted for by other known risk factors. This work highlights the importance of RSV disease in indigenous and minority populations, and identifies the need for further research to develop public health measures that can reduce health disparities.Keywords
This publication has 32 references indexed in Scilit:
- Genetic Susceptibility to Respiratory Syncytial Virus Bronchiolitis Is Predominantly Associated with Innate Immune GenesThe Journal of Infectious Diseases, 2007
- Distinct patterns of evolution between respiratory syncytial virus subgroups A and B From New Zealand isolates collected over thirty-seven yearsJournal of Medical Virology, 2006
- Hospitalization for respiratory syncytial virus among California infants: Disparities related to race, insurance, and geographyThe Journal of Pediatrics, 2006
- T280M Variation of the CX3C Receptor Gene Is Associated With Increased Risk for Severe Respiratory Syncytial Virus BronchiolitisThe Pediatric Infectious Disease Journal, 2006
- NZiDep: A New Zealand index of socioeconomic deprivation for individualsSocial Science & Medicine, 2006
- Respiratory Syncytial Virus Hospitalizations Among American Indian and Alaska Native Infants and the General United States Infant PopulationPediatrics, 2004
- Asthma prevalence in European, Maori, and Pacific children in New Zealand: ISAAC studyPediatric Pulmonology, 2004
- Impact of severe disease caused by respiratory syncytial virus in children living in developed countriesThe Pediatric Infectious Disease Journal, 2003
- Variations in bronchiolitis management between five New Zealand hospitals: Can we do better?Journal of Paediatrics and Child Health, 2003
- The management of acute bronchiolitisJournal of Paediatrics and Child Health, 1993