Adhesive bone cement containing hydroxyapatite particle as bone compatible filler

Abstract

Acrylic bone cement containing hydroxyapatite (HA) as a filler was developed using 4‐methacryloyloxyethyl trimellitate anhydride (4‐META) to promote adhesion both to bone and HA. The mechanical strengths of the cement did not decrease significantly with increasing HA in the cement by 4‐META. However, strengths decreased with increasing HA content in the absence of 4‐META. Scanning electron micrographic examination of fractured surfaces of the cement clearly showed that the HA particles adhered to the matrix resin when 4‐META was added. Thus, it was important to maintain the original mechanical strengths for 4‐META. The HA particles along the surface increased with increased HA content in the cement. The cement adhered to bone with a tensile bond strength was higher than 10 MPa.