Generation and Characterization of an Advillin-Cre Driver Mouse Line
Open Access
- 1 January 2011
- journal article
- Published by SAGE Publications in Molecular Pain
- Vol. 7 (1), 66
- https://doi.org/10.1186/1744-8069-7-66
Abstract
Progress in the somatosensory field has been restricted by the limited number of genetic tools available to study gene function in peripheral sensory neurons. Here we generated a Cre-driver mouse line that expresses Cre-recombinase from the locus of the sensory neuron specific gene Advillin. These mice displayed almost exclusive Cre-mediated recombination in all peripheral sensory neurons. As such, the Advillin-Cre-driver line will be a powerful tool for targeting peripheral neurons in future investigations.Keywords
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