The JAK-STAT pathway: summary of initial studies and recent advances.
1 January 1996
journal article
review article
Vol. 51, 391
Abstract
Polypeptides redirect cells by causing immediate changes in gene transcription. A direct connection between polypeptide receptors on the cell surface and genes in the nucleus has been provided by the recognition of the JAK-STAT pathway. Results leading to our present understanding of this pathway are reviewed.