Nonhormone-Related Histologic Findings in Postsurgical Pathology Specimens From Transgender Persons
- 1 October 2021
- journal article
- review article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 157 (3), 337-344
- https://doi.org/10.1093/ajcp/aqab143
Abstract
Objectives: The objective of this review is to characterize the literature addressing postprocedural complications in persons undergoing gender-affirming surgeries. Methods: A literature search using the OVID MEDLINE and PubMed databases was performed to identify all studies describing histologic findings in surgical pathology specimens from transgender persons from 1946 to April 2021. The studies describing postsurgical complications were categorized based on anatomic site, type of complication, study design, publication region, and date. Results: Thirty-nine studies describing postsurgical complications in transgender women were identified. The most common sites of postprocedural pathology included the breasts and neovagina, with additional studies including buttocks and thighs, cutaneous sites, and the pulmonary system. Most of the literature comprised case reports, followed by case series and comparative studies. The search did not identify any studies of complications secondary to masculinizing surgeries. Conclusions: This body of literature is small but growing. Most studies are case reports. There are significant gaps in the literature. The literature in this area is not yet mature enough to support a meta-analysis.Keywords
This publication has 45 references indexed in Scilit:
- Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7International Journal of Transgenderism, 2012
- Progressive Granulomatous Pneumonitis in Response to Cosmetic Subcutaneous Silicone Injections in a Patient With HIV-1 Infection: Case Report and Review of the LiteratureArchives of Pathology & Laboratory Medicine, 2012
- Subcutaneous silicone injection leading to multi-system organ failureClinical Toxicology, 2008
- Do Histologic Changes in the Skin-Lined Neovagina of Male-to-Female Transsexuals Really Occur?Annals of Plastic Surgery, 2007
- Genital lichen sclerosus in a case of male-to-female gender reassignmentClinical and Experimental Dermatology, 2006
- Diversion colitis in sigmoid neovaginaColorectal Disease, 2004
- Secondary Lymphoedema of the Lower Leg as an Unusual Side-Effect of a Liquid Silicone Injection in the Hips and ButtocksDermatology, 2004
- Labial Masses Following Vaginoplasty in Male Transsexuals: The Differential DiagnosisPlastic and Reconstructive Surgery, 1996
- Unfavorable Long-Term Results of Rectosigmoid NeocolpopoiesisPlastic and Reconstructive Surgery, 1995
- Unusual Breast Findings in a TranssexualAmerican Journal of Forensic Medicine & Pathology, 1987