Pathogenesis of adhesion formation/reformation: Application to reproductive pelvic surgery
- 1 January 1987
- journal article
- review article
- Published by Wiley in Microsurgery
- Vol. 8 (2), 103-107
- https://doi.org/10.1002/micr.1920080215
Abstract
Pelvic adhesions are a major contributing factor to infertility in women with tubal peritoneal disease. Surgical treatment of such adhesions often does not resolve their presence. Such postoperative adhesion formation occurs despite the use of microsurgical techniques in a wide variety of surgical adjuvants. The process of adhesion formation represents a variation of the normal healing process of the peritoneum. However, rather than normal mesothelial healing, the fibrinous mass resulting from the peritoneal defect is infiltrated by fibroblasts with subsequent adhesion formation. A description of the pathophysiology of this process is described. The current understanding of the pathologic/pathophysiologic interaction of the surgical adjuvants with this process is described.Keywords
This publication has 33 references indexed in Scilit:
- EFFECT OF INTRAPERITONEAL INSTILLATION OF 32% DEXTRAN 70 ON POSTOPERATIVE ADHESION FORMATION AFTER TUBAL SURGERYActa Obstetricia et Gynecologica Scandinavica, 1985
- Noxythiolin (Noxyflex), aprotinin (Trasylol) and peritoneal adhesion formation: An experimental study in the ratBritish Journal of Surgery, 1979
- A physiologic basis for the adhesion-free healing of deperitonealized surfacesJournal of Surgical Research, 1976
- A unifying pathogenetic mechanism in the etiology of intraperitoneal adhesionsJournal of Surgical Research, 1976
- Peritoneal adhesions and their relation to abdominal surgeryThe American Journal of Surgery, 1973
- Regeneration of parietal and visceral peritoneum a light microscopical studyBritish Journal of Surgery, 1973
- Prevention of Postoperative Intestinal Adhesions with Combined Promethazine and Dexamethasone TherapyAnnals of Surgery, 1966
- The healing of peritoneum under normal and pathological conditionsBritish Journal of Surgery, 1965
- The aetiology of post-operative abdominal adhesions an experimental studyBritish Journal of Surgery, 1962
- DEPERITONEALIZATIONAnnals of Surgery, 1949