Comparative Studies of Immobilized Enzyme Electrodes Based on the Inhibitory Effect of Nicotine on Choline Oxidase and Acetylcholinesterase
- 1 May 1992
- journal article
- chemical and-biosensors
- Published by Informa UK Limited in Analytical Letters
- Vol. 25 (5), 821-835
- https://doi.org/10.1080/00032719208020039
Abstract
The inhibitory effect of nicotine on the activity of choline oxidase immobilized on nylon net has been investigated. Nicotine was found to inhibit choline oxidase in a manner similar to its effect on acetylcholinesterase. A nicotine - sensitive probe was realised via nicotine inhibition of choline oxidase. No appreciable difference in this biosensor performance and the performance of nicotine probe incorporating acetylcholinesterase coimmobilized with choline oxidase was observed.Keywords
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