Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity
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- 28 July 2013
- journal article
- Published by Springer Science and Business Media LLC in Nature Materials
- Vol. 12 (10), 932-937
- https://doi.org/10.1038/nmat3713
Abstract
Hydrogels attract great attention as biomaterials as a result of their soft and wet nature, similar to that of biological tissues. Recent inventions of several tough hydrogels show their potential as structural biomaterials, such as cartilage. Any given application, however, requires a combination of mechanical properties including stiffness, strength, toughness, damping, fatigue resistance and self-healing, along with biocompatibility. This combination is rarely realized. Here, we report that polyampholytes, polymers bearing randomly dispersed cationic and anionic repeat groups, form tough and viscoelastic hydrogels with multiple mechanical properties. The randomness makes ionic bonds of a wide distribution of strength. The strong bonds serve as permanent crosslinks, imparting elasticity, whereas the weak bonds reversibly break and re-form, dissipating energy. These physical hydrogels of supramolecular structure can be tuned to change multiple mechanical properties over wide ranges by using diverse ionic combinations. This polyampholyte approach is synthetically simple and dramatically increases the choice of tough hydrogels for applications.Keywords
This publication has 37 references indexed in Scilit:
- Highly stretchable and tough hydrogelsNature, 2012
- Lamellar Bilayers as Reversible Sacrificial Bonds To Toughen Hydrogel: Hysteresis, Self-Recovery, Fatigue Resistance, and Crack BluntingMacromolecules, 2011
- Redox-responsive self-healing materials formed from host–guest polymersNature Communications, 2011
- A Novel Double‐Network Hydrogel Induces Spontaneous Articular Cartilage Regeneration in vivo in a Large Osteochondral DefectMacromolecular Bioscience, 2009
- Poly(vinyl alcohol)–acrylamide hydrogels as load-bearing cartilage substituteBiomaterials, 2009
- Some features of soft matter systemsSoft Matter, 2005
- Double‐Network Hydrogels with Extremely High Mechanical StrengthAdvanced Materials, 2003
- Fracture energy of gelsThe European Physical Journal E, 2000
- Swelling, Structure, and Elasticity of Polyampholyte HydrogelsLangmuir, 1999
- Theory of polyampholyte solutionsThe Journal of Chemical Physics, 1991