Comparative Analysis of Emerging B.1.1.7+E484K SARS-CoV-2 Isolates
Open Access
- 4 June 2021
- journal article
- research article
- Published by Oxford University Press (OUP) in Open Forum Infectious Diseases
- Vol. 8 (7), ofab300
- https://doi.org/10.1093/ofid/ofab300
Abstract
We report the genome of a B.1.1.7+E484K severe acute respiratory syndrome coronavirus 2 from Southeastern Pennsylvania and compare it with all high-coverage B.1.1.7+E484K genomes (n = 235) available. Analyses showed the existence of at least 4 distinct clades of this variant circulating in the United States and the possibility of at least 59 independent acquisitions of the E484K mutation.Funding Information
- Centers for Disease Control and Prevention (CDC200-2021-11102)
- Women’s Committee of the Children’s Hospital of Philadelphia
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