Metabolic Imbalance and Vitamin D Deficiency in Type 1 Diabetes in the Algerian Population
- 11 November 2019
- journal article
- research article
- Published by Bentham Science Publishers Ltd. in Endocrine, Metabolic & Immune Disorders - Drug Targets
- Vol. 19 (8), 1172-1176
- https://doi.org/10.2174/1871530319666190529113404
Abstract
Background: We aimed to assess Vitamin D levels in patients with Type 1 Diabetes (T1D) and investigate the correlation between the vitamin D and metabolic imbalance. Materiel and Methods: For our study we selected thirty-one patients with T1D without complications and fifty seven healthy controls. Diabetic patients were diagnosed using the criteria of the World Health Organization/American Diabetes Association. The Vitamin D, Parathyroid Hormone (PTH), insulin and C peptide assay were performed using chimilunescence. Glucose level, lipid profil, glycated hemoglobin (HbA1C) and ionogram were also performed. Results: Vitamin D, HbA1c and Gly levels were found to be significantly in T1D patients than in controls (P 0. 05) and the results show a non significant difference of cholesterol total potassium, sodium, phosphor and calcium concentration averages. Conclusion: Our results indicate that deficiency of VD is associated with increased risk of T1DM in Algerian population.Keywords
This publication has 21 references indexed in Scilit:
- Variants of Interleukin-22 Gene Confer Predisposition to Autoimmune Thyroid DiseaseInternational Journal of Endocrinology, 2017
- Thyroid eye disease: a reviewClinical and Experimental Optometry, 2017
- Graves’ Ophthalmopathy: VISA versus EUGOGO Classification, Assessment, and ManagementJournal of Ophthalmology, 2015
- Th1, Th2, and Th17 Cytokine Involvement in Thyroid Associated OphthalmopathyDisease Markers, 2015
- Thyroid eye disease for the primary care physicianDisease-a-Month, 2014
- Graves Orbitopathy: Update on Diagnosis and TherapySouthern Medical Journal, 2014
- Association of single-nucleotide polymorphisms in the STAT3 gene with autoimmune thyroid disease in Chinese individualsFunctional & Integrative Genomics, 2013
- Inflammatory cytokine profiles in the tears of thyroid-associated ophthalmopathyAlbrecht von Graefes Archiv für Ophthalmologie, 2011
- Thyroid eye diseaseBMJ, 2009
- Consensus Statement of the European Group on Graves' Orbitopathy (EUGOGO) on Management of Graves' OrbitopathyThyroid®, 2008