Mutagenicity testing of ST-film with the Ames test, chromosome test in vitro and micronucleus test in female mice.

Abstract

The mutagenicity of ST-film and its components polyoxyethylenenonylether (NP-10) and polyvinylalcohol (PVAL) were studied by a reverse mutation test in S. typhimurium (Ames test), a chromosome test in cultured Chinese hamster V 79 cells and a micronucleus test in female mice. The results obtained from these test systems were all negative. Thus, it may be concluded that ST-film is not mutagenic either in vitro or in vivo mutagenicity testing systems.