The mass production of systematic reviews about COVID‐19: An analysis of PROSPERO records
Open Access
- 17 February 2021
- journal article
- research article
- Published by Wiley in Journal of Evidence-Based Medicine
- Vol. 14 (1), 56-64
- https://doi.org/10.1111/jebm.12426
Abstract
Objective This study aimed to assess the characteristics of different designs of systematic reviews (SRs) registered in the International Prospective Register of Systematic Reviews (PROSPERO) about COVID‐19. Methods The search was performed in the PROSPERO database using the strategy proposed by the database and considered only human studies. The last date of the search was April 27, 2020. Full text of all records was accessed, and data were extracted by a single researcher, which was further double‐checked by another researcher. A descriptive analysis was performed considering record characteristics using tables. Results We included 564 records from which the vast majority were registered as SRs (n = 513, 91%). In general, we found poor reporting and missing or confusing information, since 84% of the records (n = 474) did not report the full search that would be adopted, 16% (n = 90) did not report clearly the databases that would be used, and 49.1% (n = 277) did not report the number of primary outcomes. The main focus of most of the records involved clinical, epidemiological, complication, and laboratory characteristics (n = 173, 30.7%) or the treatment of COVID‐19 (n = 138, 24.5%). Conclusion A large number of SRs about COVID‐19 have been conducted, and many of the assessed records were poorly reported and would be difficult to replicate. Besides, collected data points to an epidemic of redundant reviews on COVID‐19.Keywords
This publication has 18 references indexed in Scilit:
- Methodological challenges in studying the COVID-19 pandemic crisisJournal of Clinical Epidemiology, 2020
- Potential use of hydroxychloroquine, ivermectin and azithromycin drugs in fighting COVID-19: trends, scope and relevanceNew Microbes and New Infections, 2020
- Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational studyTravel Medicine and Infectious Disease, 2020
- Discrepancies in meta-analyses answering the same clinical question were hard to explain: a meta-epidemiological studyJournal of Clinical Epidemiology, 2019
- A third of systematic reviews changed or did not specify the primary outcome: a PROSPERO register studyJournal of Clinical Epidemiology, 2016
- How to reduce unnecessary duplication: use PROSPEROBJOG: An International Journal of Obstetrics and Gynaecology, 2014
- The nuts and bolts of PROSPERO: an international prospective register of systematic reviewsSystematic Reviews, 2012
- Fundamentals of Clinical TrialsPublished by Springer Science and Business Media LLC ,2010