Degradable metallic biomaterials: Design and development of Fe–Mn alloys for stents
- 12 May 2009
- journal article
- research article
- Published by Wiley in Journal of Biomedical Materials Research Part A
- Vol. 93A (1), 1-11
- https://doi.org/10.1002/jbm.a.32224
Abstract
Designing materials having suitable mechanical properties and targeted degradation behavior is the key for the development of biodegradable materials for medical applications, including stents. A series of Fe–Mn alloys was developed with the objective to obtain mechanical properties similar to those of stainless steel 316L and degradation behavior more suited than pure iron. Four alloys with Mn content ranging between 20 and 35 wt % were compared in this study. Their microstructure, mechanical properties, magnetic properties as well as degradation behavior were carefully investigated. Results show that their microstructure is mainly composed of γ phase with the appearance of ϵ phase in alloys having a lower Mn content. The yield strength and elongation of alloys was comprised between 234 MPa and 32% for Fe-35%Mn alloy to 421 MPa and 7.5% for the Fe-20%Mn alloy. All alloys show similar magnetic susceptibility (∼1.8 × 10−7 m3/kg) in the quenched condition. This magnetic susceptibility remains constant after plastic deformation for all the tested alloys except for the Fe-20%Mn alloy. The corrosion rate was higher than pure iron. Among the alloys studied in this work, the Fe-35%Mn alloy shows mechanical properties and degradation behavior closely approaching those required for biodegradable stents application. © 2009 Wiley Periodicals, Inc. J Biomed Mater Res 2010Keywords
This publication has 43 references indexed in Scilit:
- Development of Degradable Fe-35Mn Alloy for Biomedical ApplicationAdvanced Materials Research, 2006
- Coronary-Artery StentsThe New England Journal of Medicine, 2006
- In vivo corrosion of four magnesium alloys and the associated bone responseBiomaterials, 2005
- Magnetic investigation of the effect of α′-martensite on the properties of austenitic stainless steelJournal of the American Academy of Dermatology, 2005
- Effect of nitrogen on damping, mechanical and corrosive properties of Fe–Mn alloysMaterials Science and Engineering: A, 2002
- Evaluation of the carcinogenic risks to humans associated with surgical implants and other foreign bodies — a report of an IARC Monographs Programme MeetingEuropean Journal of Cancer, 2000
- An assessment of the Fe-Mn systemCalphad, 1989
- Intravascular Stents to Prevent Occlusion and Re-Stenosis after Transluminal AngioplastyThe New England Journal of Medicine, 1987
- A study of γ → ε phase transformation in FeMn alloys induced by high pressure and plastic deformationScripta Metallurgica, 1978
- Constitution of Binary AlloysJournal of the Electrochemical Society, 1958