Recent development of direct asymmetric functionalization of inert C–H bonds
- 6 December 2013
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 4 (12), 6173-6214
- https://doi.org/10.1039/c3ra46996d
Abstract
The area of direct asymmetric functionalization of inert C–H bonds has attracted considerable attention in recent years. To realize this type of challenging but promising transformations, a lot of strategies have emerged including asymmetric C–H bond insertion by metal carbenoids or analogs, cross dehydrogenative coupling, [1,5]-hydride transfer, C–H bond functionalization involving a transient metal–carbon species and other miscellaneous methods. This review is intended to summarize and discuss the most recent developments (contributions mainly after 2009) within this area.Keywords
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