A monoclonal antibody for large-scale purification of human leukocyte interferon
- 1 June 1980
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 285 (5765), 446-450
- https://doi.org/10.1038/285446a0
Abstract
A clone of hybrid myelomas (NK2), secreting a mouse monoclonal antibody to human leukocyte interferon, has been isolated. The antibody neutralizes the antiviral activity of the interferon and, when covalently attached to a solid support and used as an immunoadsorbent, allows interferon purification of up to 5,000-fold in a single step.This publication has 28 references indexed in Scilit:
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