Chemotherapy and interferon-α treatment of Erdheim-chester disease
- 29 June 2010
- journal article
- case report
- Published by Wiley in Pediatric Blood & Cancer
- Vol. 55 (4), 745-747
- https://doi.org/10.1002/pbc.22636
Abstract
Erdheim–Chester disease (ECD) is a rare non‐Langerhans cell histiocytosis of an unknown origin. The prognosis of ECD is variable, and it mainly depends on the involved anatomic sites. The treatment modalities have not been standardized. Interferon‐α (IFN) has been reported to be effective in the management of ECD. We report here on an uncommon case with ECD in a 17‐year‐old female who had multiple lesions in the whole body and she was treated with chemotherapy and IFN. She has remained disease‐free for 2 years after the completion of treatment. Pediatr Blood Cancer. 2010;55:745–747.Keywords
This publication has 12 references indexed in Scilit:
- Erdheim-Chester Disease in ChildhoodJournal of Pediatric Hematology/Oncology, 2009
- Variability in the efficacy of interferon‐α in Erdheim‐Chester disease by patient and site of involvement: Results in eight patientsArthritis & Rheumatism, 2006
- Successful treatment of Erdheim-Chester disease, a non–Langerhans-cell histiocytosis, with interferon-αBlood, 2005
- Cardiovascular Involvement, an Overlooked Feature of Erdheim-Chester DiseaseMedicine, 2004
- Improvement of Erdheim?Chester disease in two patients by sequential treatment with vinblastine and mycophenolate mofetilClinical Rheumatology, 2004
- Erdheim–Chester disease in a childMedical and Pediatric Oncology, 2003
- Interferon-alpha therapy, protein kinase C-alpha and Langerhans cell histiocytosis.Medical and Pediatric Oncology, 2003
- Erdheim-Chester Disease: Case Report, PCR-Based Analysis of Clonality, and Review of LiteratureLaboratory Investigation, 2002
- IFN‐α enhances CD40 ligand‐mediated activation of immature monocyte‐derived dendritic cellsInternational Immunology, 2002
- Erdheim-Chester Disease Clinical and Radiologic Characteristics of 59 CasesMedicine, 1996