Chronic Thromboembolic Pulmonary Arterial Hypertension
- 1 April 2004
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Thoracic Imaging
- Vol. 19 (2), 67-73
- https://doi.org/10.1097/00005382-200404000-00001
Abstract
Pulmonary thromboendarterectomy is the treatment of choice for patients with chronic thromboembolic pulmonary arterial hypertension (CTEPH). Some patients do poorly after this procedure and may be better candidates for heart-lung transplant. The purpose of this study was to correlate preoperative findings on helical contrast-enhanced computed tomography (CT) with surgical outcome. Thirty-seven patients (mean age 52.9, range 22-71) who underwent pulmonary thromboendarterectomy and had preoperative helical contrast-enhanced CT followed by High Resolution CT (HRCT) scans were included in the study. The CTs were evaluated for the presence of central and segmental disease and for the presence of mosaic perfusion pattern. The presence of central disease, as well as the presence of segmental disease, correlated negatively with the postoperative mean pulmonary arterial pressure [r(c) = -0.401, P = 0.015, r(s) = -0.38, P = 0.024)] and the pulmonary vascular resistance [(r(c) = -0.37, P = 0.027, r(s) = -0.39, P = 0.019]. No correlation was found between the clinical variables and the presence of mosaic perfusion pattern. Patients with CTEPH and evidence of chronic PE in the central or segmental pulmonary arteries have a better clinical outcome after pulmonary thromboendarterectomy than patients without these findings. The presence of mosaic perfusion pattern is not helpful in predicting postoperative outcome.Keywords
This publication has 19 references indexed in Scilit:
- Chronic Thromboembolic Pulmonary HypertensionThe New England Journal of Medicine, 2001
- CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSIONClinics in Chest Medicine, 2001
- Predictors of Patient Response to Pulmonary ThromboendarterectomyAmerican Journal of Roentgenology, 2000
- Chronic thromboembolic pulmonary hypertension: CT findings.American Journal of Roentgenology, 1998
- Accuracy of high-resolution CT in identifying chronic pulmonary thromboembolic disease.American Journal of Roentgenology, 1996
- Profile of paediatric patients with pulmonary hypertension judged by responsiveness to vasodilators.Heart, 1993
- Role of CT in Chronic Pulmonary EmbolismJournal of Computer Assisted Tomography, 1993
- Pulmonary Vascular Lesions Occurring in Patients With Chronic Major Vessel Thromboembolic Pulmonary HypertensionSocial psychiatry. Sozialpsychiatrie. Psychiatrie sociale, 1993
- Computed Tomography Assessment of Ground-Glass OpacityJournal of Thoracic Imaging, 1993
- Chronic major-vessel thromboembolic pulmonary hypertension.Circulation, 1990