Prevention of Human Diabetic Ketoacidosis by Somatostatin
- 8 May 1975
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 292 (19), 985-989
- https://doi.org/10.1056/nejm197505082921901
Abstract
To evaluate the role of glucagon in the pathogenesis of diabetic ketoacidosis in man, we studied the effect of suppression of glucagon secretion by somatostatin on changes in plasma β-hydroxybutyrate and glucose concentrations (as well as changes in their precursors) after acute withdrawal of insulin from seven patients with juvenile-type diabetes.Keywords
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