Thiazole–aminopiperidine hybrid analogues: Design and synthesis of novel Mycobacterium tuberculosis GyrB inhibitors
- 3 October 2013
- journal article
- research article
- Published by Elsevier BV in European Journal of Medicinal Chemistry
- Vol. 70, 143-153
- https://doi.org/10.1016/j.ejmech.2013.09.025
Abstract
No abstract availableKeywords
Funding Information
- Council of Scientific and Industrial Research (01 (2394)/10/EMR-II)
This publication has 25 references indexed in Scilit:
- Exploring novel KDR inhibitors based on pharmaco-informatics methodologySAR and QSAR in Environmental Research, 2013
- Design, Synthesis, and Structure–Activity Correlations of Novel Dibenzo[b,d]furan, Dibenzo[b,d]thiophene, and N-Methylcarbazole Clubbed 1,2,3-Triazoles as Potent Inhibitors of Mycobacterium tuberculosisJournal of Medicinal Chemistry, 2012
- Pyrrolamide DNA gyrase inhibitors: Optimization of antibacterial activity and efficacyBioorganic & Medicinal Chemistry Letters, 2011
- Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyraseBioorganic & Medicinal Chemistry Letters, 2010
- The art of the chemical probeNature Chemical Biology, 2010
- Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense ExpressionPLOS ONE, 2009
- Drug hybridization strategies: before or after lead identification?Expert Opinion on Drug Discovery, 2009
- Novel Dual-Targeting Benzimidazole Urea Inhibitors of DNA Gyrase and Topoisomerase IV Possessing Potent Antibacterial Activity: Intelligent Design and Evolution through the Judicious Use of Structure-Guided Design and Stucture−Activity RelationshipsJournal of Medicinal Chemistry, 2008
- Extra Precision Glide: Docking and Scoring Incorporating a Model of Hydrophobic Enclosure for Protein−Ligand ComplexesJournal of Medicinal Chemistry, 2006
- In silico fragment-based discovery of indolin-2-one analogues as potent DNA gyrase inhibitorsBioorganic & Medicinal Chemistry Letters, 2005