REVISED DEFINITION OF PRE-ECLAMPSIA
- 1 April 1988
- journal article
- research article
- Published by Elsevier BV in The Lancet
- Vol. 331 (8589), 809-812
- https://doi.org/10.1016/s0140-6736(88)91667-4
Abstract
Different measures of raised blood pressure were analysed in 16211 singleton pregnancies to determine to most effective way of identifying pre-eclampsia. Increments from baseline in the first half of pregnancy were considered as well as absolute levels. A combination of a high maximum diastolic pressure with a large increase from baseline was better for identifying a group with pre-eclamptic features than either measurement on its own. A first diastolic pressure below 90 mm Hg, a subsequent increase of at least 25 mm Hg, and a maximum reading of at least 90 mm Hg gave appropriate criteria. These were applied to a second set of 15,624 singleton pregnancies and successfully identified a group with pre-eclamptic features. Fewer women were identified as pre-eclamptic than with criteria modified from an existing definition widely used in Britain. The women excluded by the new criteria had the features of mild chronic hypertension rather than pre-eclampsia. The new definition is simple to use but like all other definitions of pre-eclampsia cannot be precise.This publication has 7 references indexed in Scilit:
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