Lipoatrophic panniculitis and chromosome 10 abnormality
- 1 May 2000
- journal article
- case report
- Published by Wiley in British Journal of Dermatology
- Vol. 142 (5), 1034-1039
- https://doi.org/10.1046/j.1365-2133.2000.03493.x
Abstract
We report a 3‐year‐old girl with a 12‐month history of an acquired lipoatrophy that was rapidly progressive. Her karyotype revealed additional material on chromosome 10 at the 10q26 location. The human pancreatic lipase gene maps to chromosome 10q24–26, and we postulate an association. Lipoatrophic panniculitis describes the panniculitides in which atrophy is a feature. The classification of these diseases is confusing in the literature and the precise diagnosis still relies on a combination of clinical and laboratory assessment. Our finding of a chromosomal abnormality on chromosome 10q26 has not been described previously.Keywords
This publication has 14 references indexed in Scilit:
- Pancreatic panniculitisJournal of the American Academy of Dermatology, 1995
- The clinical spectrum of lipoatrophic panniculitis encompasses connective tissue panniculitisBritish Journal of Dermatology, 1993
- Assignment of human pancreatic lipase gene (PNLIP) to chromosome 10q24–q26Genomics, 1991
- Adult lipophagic atrophic panniculitisBritish Journal of Dermatology, 1991
- Dermatomyositis associated with multifocal lipoatrophyJournal of the American Academy of Dermatology, 1990
- Lipophagic panniculitis of childhoodJournal of the American Academy of Dermatology, 1989
- Panniculitis associated with a pancreas divisumJournal of the American Academy of Dermatology, 1986
- Carpal tunnel syndrome in cutaneous connective tissue disease: Generalized morphea, lichen sclerosus, fasciitis, discoid lupus erythematosus, and lupus panniculitisJournal of the American Academy of Dermatology, 1982
- The histopathology of lupus erythematosus panniculitisJournal of the American Academy of Dermatology, 1981
- Lupus panniculitis (profundus)The Journal of Pediatrics, 1981