NF-κB and p53 Are the Dominant Apoptosis-inducing Transcription Factors Elicited by the HIV-1 Envelope
Open Access
- 1 March 2004
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 199 (5), 629-640
- https://doi.org/10.1084/jem.20031216
Abstract
The coculture of cells expressing the HIV-1 envelope glycoprotein complex (Env) with cells expressing CD4 results into cell fusion, deregulated mitosis, and subKeywords
This publication has 41 references indexed in Scilit:
- Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDSJournal of General Virology, 2003
- Apoptosis as an HIV strategy to escape immune attackNature Reviews Immunology, 2003
- Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastropheCell Death & Differentiation, 2002
- Live or let die: the cell's response to p53Nature Reviews Cancer, 2002
- NF-κB in cancer: from innocent bystander to major culpritNature Reviews Cancer, 2002
- HIV induces lymphocyte apoptosis by a p53‐initiated, mitochondrial‐mediated mechanismThe FASEB Journal, 2000
- Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complexCell Death & Differentiation, 2000
- Apoptosis of Syncytia Induced by the HIV-1–Envelope Glycoprotein Complex: Influence of Cell Shape and SizeExperimental Cell Research, 2000
- Tumor suppressor p53 is a direct transcriptional activator of the human bax geneCell, 1995
- p53 Mutations in Human CancersScience, 1991