The impact of first-trimester screening on AMA patients' uptake of invasive testing
- 1 May 2005
- journal article
- research article
- Published by Wiley in Prenatal Diagnosis
- Vol. 25 (5), 350-353
- https://doi.org/10.1002/pd.1144
Abstract
Objective Prenatal testing for AMA includes invasive procedures such as CVS and amniocentesis, which have risks. We sought to determine the effects of first‐trimester screening (FTS) on referrals for genetic counseling and patients' decisions to pursue invasive testing after FTS was offered in 2002. Methods We compared AMA patients presenting for prenatal care who underwent early genetic counseling (t‐test and chi‐square tests. Results In 2001, 552 AMA women enrolled in prenatal care; 68 presented for early genetic counseling. In 2003, 728 AMA women enrolled in prenatal care; 172 presented for early genetic counseling. More counseled women chose genetic testing in 2003 than in 2001 (95% vs 79%, p < 0.01). More patients elected an invasive procedure in 2001 compared to 2003 (71% vs 26%, p < 0.01). Conclusion Availability of FTS results in more AMA women having early prenatal genetic counseling and choosing some form of genetic testing. Such women are less likely to choose invasive tests than those without access to FTS. Copyright © 2005 John Wiley & Sons, Ltd.Keywords
This publication has 11 references indexed in Scilit:
- Changes in the Utilization of Prenatal DiagnosisObstetrics & Gynecology, 2004
- Cost utility of prenatal diagnosis and the risk-based thresholdThe Lancet, 2004
- First-Trimester Screening for Trisomies 21 and 18The New England Journal of Medicine, 2003
- Psychosocial Genetic Counseling in the Post‐Nondirective Era: A Point of ViewJournal of Genetic Counseling, 2003
- Decisions about amniocentesis by advanced maternal age patients following maternal serum screening may not always correlate clinically with screening results: Need for improvement in informed consent processAmerican Journal of Medical Genetics, 2002
- Sonographic markers of fetal trisomies: second trimester.Journal of Ultrasound in Medicine, 2001
- Update and Review: Maternal Serum ScreeningJournal of Genetic Counseling, 1997
- Amniocentesis in sociocultural perspectiveJournal of Genetic Counseling, 1993
- Chromosome findings in 2,500 second trimester amniocentesesAmerican Journal of Medical Genetics, 1980
- Genetic counseling — the postcounseling period: II. Making reproductive choicesAmerican Journal of Medical Genetics, 1979