A survey was conducted (n = 1,216) to evaluate the level of knowledge about basic facts of genetics and attitudes toward gene tests among the Finnish population. Our results show that a majority of the Finnish population generally approved of gene tests. Well over half of the respondents believed that genetic testing will have positive consequences, but many also had worries related to the development of gene tests. We showed that there was an association between knowledge and attitudes, but better knowledge did not simply lead to unambiguous acceptance. Among those with the highest level of knowledge there was in many respects both more enthusiasm and more skepticism than among those with the lowest level of knowledge. Those with a low level of knowledge had more difficulties in taking a stance toward attitude statements. In general, steps should be taken, first, to increase citizens' capabilities to seek and understand information about genetics and specific diseases when faced with a need for it. Second, steps should be taken to provide citizens with tools to perceive and discuss potential ethical and social problems, which development of gene technology, genetic testing, and screening bring along. Sites for these enterprises could be the biology school curriculum, genetic counseling, media, as well as health education and health communication in general.