Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor
- 9 March 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 223 (4640), 1079-1082
- https://doi.org/10.1126/science.6320373
Abstract
The complete amino acid sequence of rat transforming growth factor type 1 has been determined. This growth factor, obtained from retrovirus-transformed fibroblasts, is structurally and functionally related to mouse epidermal growth factor and human urogastrone. Production of this polypeptide by various neoplastic cells might contribute to the continued expression of the transformed phenotype.This publication has 26 references indexed in Scilit:
- Structure of a Mouse Submaxillary Messenger RNA Encoding Epidermal Growth Factor and Seven Related ProteinsScience, 1983
- The biochemistry and physiology of the receptor-kinase for epidermal growth factorMolecular and Cellular Endocrinology, 1983
- Cellular responsiveness to growth factors correlates with a cell's ability to express the transformed phenotypeCell, 1983
- Nucleotide sequence of epidermal growth factor cDNA predicts a 128,000-molecular weight protein precursorNature, 1983
- Transformation Induced by Abelson Murine Leukemia Virus Involves Production of a Polypeptide Growth FactorScience, 1982
- Properties of a sarcoma‐growth‐factor‐like peptide from cells transformed by a temperature‐sensitive sarcoma virusJournal of Cellular Physiology, 1981
- Autocrine Secretion and Malignant Transformation of CellsNew England Journal of Medicine, 1980
- Schwann cell growth factorsCell, 1978
- Isolation and structure of urogastrone and its relationship to epidermal growth factorNature, 1975
- Preparation of Iodine-131 Labelled Human Growth Hormone of High Specific ActivityNature, 1962