Inhibition of Src Family Kinases Blocks Epidermal Growth Factor (EGF)-induced Activation of Akt, Phosphorylation of c-Cbl, and Ubiquitination of the EGF Receptor
Open Access
- 1 July 2002
- journal article
- Published by Elsevier BV
- Vol. 277 (28), 24967-24975
- https://doi.org/10.1074/jbc.m201026200
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- The Proto-oncogene p120CblIs a Downstream Substrate of the Hck Protein-Tyrosine KinaseBiochemical and Biophysical Research Communications, 1999
- Differential Signaling after β1 Integrin Ligation Is Mediated Through Binding of CRKL to p120 and p110Published by Elsevier BV ,1997
- Characterization of Cbl tyrosine phosphorylation and a Cbl-Syk complex in RBL-2H3 cells.The Journal of Experimental Medicine, 1996
- Specific Association of Tyrosine-phosphorylated c-Cbl with Fyn Tyrosine Kinase in T CellsJournal of Biological Chemistry, 1996
- Tyrosine Phosphorylation of Cbl upon Epidermal Growth Factor (EGF) Stimulation and Its Association with EGF Receptor and Downstream Signaling ProteinsJournal of Biological Chemistry, 1996
- p120 Is a Cytosolic Adapter Protein That Associates with Phosphoinositide 3-Kinase in Response to Epidermal Growth Factor in PC12 and Other CellsJournal of Biological Chemistry, 1996
- Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase InhibitorJournal of Biological Chemistry, 1996
- Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth FactorScience, 1995
- SH2 domains recognize specific phosphopeptide sequencesCell, 1993
- Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu OncogeneScience, 1987