Vivo-Morpholinos: A Non-Peptide Transporter Delivers Morpholinos into a Wide Array of Mouse Tissues
Open Access
- 1 December 2008
- journal article
- Published by Taylor & Francis Ltd in BioTechniques
- Vol. 45 (6), 613-623
- https://doi.org/10.2144/000113005
Abstract
We have developed a new transporter structure that provides effective delivery ofMorpholino antisense oligomers into a wide variety of tissues in living mice. This transporter comprises a dendritic...This publication has 31 references indexed in Scilit:
- Achieving targeted and quantifiable alteration of mRNA splicing with Morpholino oligosBiochemical and Biophysical Research Communications, 2007
- Endosome trapping limits the efficiency of splicing correction by PNA-oligolysine conjugatesJournal of Controlled Release, 2006
- Intracellular Uptake and Inhibition of Gene Expression by PNAs and PNA−Peptide ConjugatesBiochemistry, 2004
- DELIVERY OF PROTEINS AND PEPTIDES INTO LIVE CELLS BY MEANS OF PROTEIN TRANSDUCTION DOMAINS: POTENTIAL APPLICATION TO ORGAN AND CELL TRANSPLANTATIONTransplantation, 2004
- Caveolae-Mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real timeMolecular Therapy, 2003
- Cell-penetrating Peptides: A REEVALUATION OF THE MECHANISM OF CELLULAR UPTAKEPublished by Elsevier BV ,2003
- Translocation of Branched-Chain Arginine Peptides through Cell Membranes: Flexibility in the Spatial Disposition of Positive Charges in Membrane-Permeable PeptidesBiochemistry, 2002
- Conjugates of Antisense Oligonucleotides with the Tat and Antennapedia Cell-Penetrating Peptides: Effects on Cellular Uptake, Binding to Target Sequences, and Biologic ActionsPharmaceutical Research, 2002
- The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transportersProceedings of the National Academy of Sciences of the United States of America, 2000
- Antisense inhibition of P-glycoprotein expression using peptide–oligonucleotide conjugatesBiochemical Pharmacology, 2000