Peroxynitrite Induces Destruction of the Tetrahydrobiopterin and Heme in Endothelial Nitric Oxide Synthase: Transition from Reversible to Irreversible Enzyme Inhibition
- 25 February 2010
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 49 (14), 3129-3137
- https://doi.org/10.1021/bi9016632
Abstract
No abstract availableKeywords
This publication has 59 references indexed in Scilit:
- Characterization of the Peroxidase Mechanism upon Reaction of Prostacyclin Synthase with Peracetic Acid. Identification of a Tyrosyl Radical IntermediateBiochemistry, 2009
- In Vivo Atherosclerotic Plaque Characterization Using Magnetic Susceptibility Distinguishes Symptom-Producing PlaquesJACC: Cardiovascular Imaging, 2008
- Peroxynitrite mediates the failure of neutrophil migration in severe polymicrobial sepsis in miceBritish Journal of Pharmacology, 2007
- Superoxide, peroxynitrite and oxidative/nitrative stress in inflammationBiochemical Society Transactions, 2006
- Structure of a Loose Dimer: an Intermediate in Nitric Oxide Synthase AssemblyJournal of Molecular Biology, 2005
- Reaction of Ferric Cytochrome P450cam with PeracidsOnline Journal of Public Health Informatics, 2005
- Oxidation of Tetrahydrobiopterin by Peroxynitrite: Implications for Vascular Endothelial FunctionBiochemical and Biophysical Research Communications, 1999
- Nitric Oxide-Generated P420 Nitric Oxide Synthase: Characterization and Roles for Tetrahydrobiopterin and Substrate in Protecting against or Reversing the P420 ConversionBiochemistry, 1999
- Effects of Various Imidazole Ligands on Heme Conformation in Endothelial Nitric Oxide SynthaseBiochemistry, 1998
- Cysteine 99 of Endothelial Nitric Oxide Synthase (NOS-III) Is Critical for Tetrahydrobiopterin-Dependent NOS-III Stability and ActivityBiochemical and Biophysical Research Communications, 1995