Sexual Function After Treatment for Rectal Cancer: A Review
- 1 January 2011
- journal article
- review article
- Published by Ovid Technologies (Wolters Kluwer Health) in Diseases of the Colon & Rectum
- Vol. 54 (1), 113-125
- https://doi.org/10.1007/dcr.0b013e3181fb7b82
Abstract
Sexual function is one element of QOL that may be significantly altered following treatment for rectal cancer, but the incidence and contributing risk factors are generally poorly understood. Nevertheless, the impact of rectal cancer therapy on sexual function should be conveyed to patients preoperatively. In addition to helping patients evolve realistic expectations, it will help clinicians identify those for whom interventions may be appropriate. In the past 10 years, there has been an increase in the number of studies reporting sexual dysfunction following rectal cancer treatment. However, these studies are difficult to interpret collectively for a variety of reasons. Most importantly, sexual dysfunction lacks a standardized definition, which leads to poor comparability between studies. The best inclusive definitions describe sexual dysfunction as a collection of distinct symptoms, which differ for men and women. The absence of sexual activity is sometimes used as a surrogate for sexual dysfunction, but this is confounded by an individual's desire and opportunity for sexual activity, and may not be an accurate reflection of physiologic functionality. Additional factors complicating assimilation of studies include the absence of baseline data, missing data, small sample sizes, and heterogeneity in use of validated and nonvalidated instruments. The purpose of this article is to systematically review the contemporary literature reporting sexual function after rectal surgery to determine the overall risk of sexual dysfunction, evaluate possible contributing factors, and identify questions that should be addressed in future studies.Keywords
This publication has 47 references indexed in Scilit:
- A Meta-Analysis of Quality of Life for Abdominoperineal Excision of Rectum versus Anterior Resection for Rectal CancerAnnals of Surgical Oncology, 2007
- Prevalence of Male and Female Sexual Dysfunction Is High Following Surgery for Rectal CancerAnnals of Surgery, 2005
- The Female Sexual Function Index (FSFI): Cross-Validation and Development of Clinical Cutoff ScoresJournal of Sex & Marital Therapy, 2005
- Assessment of Sexual and Voiding Function After Total Mesorectal Excision With Pelvic Autonomic Nerve Preservation in Males With Rectal CancerDiseases of the Colon & Rectum, 2002
- Prospective analysis of quality of life and survival following mesorectal excision for rectal cancerBritish Journal of Surgery, 2001
- Quality of life in patients with urinary diversion after operation for locally advanced rectal cancerEuropean Journal of Surgical Oncology, 2001
- Phase II clinical trial of preoperative combined chemoradiation for T3 and T4 resectable rectal cancerDiseases of the Colon & Rectum, 2001
- A prospective study on radical and nerve-preserving surgery for rectal cancer in The NetherlandsEuropean Journal of Surgical Oncology, 2000
- Sphincter-sparing surgery after preoperative radiotherapy for low rectal cancers: feasibility, oncologic results and quality of life outcomesBritish Journal of Cancer, 2000
- The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunctionUrology, 1997