The Spectrum of Mucin-Producing Adenocarcinoma of the Pancreas
- 1 August 2000
- journal article
- Published by Ovid Technologies (Wolters Kluwer Health) in Pancreas
- Vol. 21 (2), 147-151
- https://doi.org/10.1097/00006676-200008000-00007
Abstract
The clinical distinction between cystic and mucinous carcinomas of the pancreas has been poorly defined. Therefore we sought to stratify the entity known as pancreatic mucinous adenocarcinoma based on pathologic and clinical criteria. Clinical data and pathology specimens were reviewed for patients (n = 40) who had been diagnosed as having mucin-producing pancreatic adenocarcinoma and had undergone either resection or intraoperative biopsy of their pancreatic tumor during a 40-year period at the UCLA Medical Center. Based on histologic criteria, three distinct classes of pancreatic adenocarcinoma were identified: mucinous noncystic (colloid) adenocarcinoma (group I), mucinous cystadenocarcinoma (group II), and ductal adenocarcinoma (group III). Based on clinical behavior, groups I and III were indistinguishable. Compared to patients from groups I and III, those from group II were younger, more likely to be female, and had a better prognosis. Among mucin-producing adenocarcinomas of the pancreas, mucinous noncystic adenocarcinoma and ductal adenocarcinoma share similar clinical features, whereas true cystic lesions represent a distinct clinical entity.Keywords
This publication has 7 references indexed in Scilit:
- Mucin-Producing Neoplasms of the PancreasAnnals of Surgery, 1996
- Cystic Tumors of the PancreasSurgical Clinics of North America, 1995
- Spectrum of cystic tumors of the pancreasThe American Journal of Surgery, 1992
- Mucin-producing tumor of the pancreasCancer, 1991
- Cystic Tumors of the PancreasAnnals of Surgery, 1990
- Morphological study of 391 cases of exocrine pancreatic tumours with special reference to the classification of exocrine pancreatic carcinomaThe Journal of Pathology, 1985
- Carcinoma of the exocrine pancreas: Pathologic aspectsJournal of Surgical Oncology, 1975