Prosthetic Joint Infections: Bane of Orthopedists, Challenge for Infectious Disease Specialists
Top Cited Papers
Open Access
- 1 May 2003
- journal article
- Published by Oxford University Press (OUP) in Clinical Infectious Diseases
- Vol. 36 (9), 1157-1161
- https://doi.org/10.1086/374554
Abstract
Prosthetic joint infections (PJIs) occur in ∼1.5%–2.5% of all primary hip or knee arthroplasties. The mortality rate attributed to PJIs may be as high as 2.5%. Substantial morbidity is associated with a loss of mobility, although this is temporary. The costs associated with a single episode of PJI are ∼$50,000 per episode, exclusive of lost wages. Risk factors that increase the occurrence of PJI include revision arthroplasty, time in the operating room, postoperative surgical site infection, and malignancy. Pain is the most consistent symptom. Staphylococcus species are the most common organisms isolated from PJI sites. Two-stage revision is superior to single-stage revision or to debridement with prosthesis retention. Long-term antibiotic suppression and/or arthrodesis are useful for patients too frail to undergo extensive surgery. Using an optimal approach, recurrent infection occurs in <10% of previously infected joints.Keywords
This publication has 30 references indexed in Scilit:
- Septic Joint Replacement: An Orthopedic PerspectiveClinical Infectious Diseases, 2002
- Infection in Total Knee ReplacementClinical Orthopaedics and Related Research, 2001
- Efficacy of combined technetium-99m sulfur colloid/indium-111 leukocyte scans to detect infected total hip and knee arthroplastiesThe Journal of Arthroplasty, 2001
- Clinical Effectiveness and Cost-Effectiveness of 2 Management Strategies for Infected Total Hip Arthroplasty in the ElderlyClinical Infectious Diseases, 2001
- Joint prosthetic infections: A success storyActa Orthopaedica, 2001
- Infected total knee arthroplasty treated by arthroscopic irrigation and débridementThe Journal of Arthroplasty, 2000
- Risk Factors for Prosthetic Joint Infection: Case‐Control StudyClinical Infectious Diseases, 1998
- 2-Stage Reimplantation for Infected Total Knee ReplacementClinical Orthopaedics and Related Research, 1996
- The infected knee arthroplasty: A 6-year follow-up of 357 casesActa Orthopaedica, 1991
- Medical and Surgical Treatment of the Septic Hip with One-stage Revision ArthroplastyClinical Orthopaedics and Related Research, 1982